Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape

by Penny L Moore, Elin S Gray, C Kurt Wibmer et al.
Nature Medicine – Advance Online Publication, 21 October 2012

6 pp. 654 kB:
http://health-e.org.za/documents/65ed0a18ee383f46bfbaca3f6d0151ec.pdf

The study describes how a unique change in the outer covering of the virus found in two HIV infected South African women enabled them to make potent antibodies which are able to kill up to 88% of HIV types from around the world. The discovery, described as “groundbreaking” provides an important new approach that could be useful in making an AIDS vaccine, according to the researchers.

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