Systematic review of current and emerging strategies for reducing morbidity from malaria in sickle cell disease

by Ehimen C. Aneni, Davidson H. Hamer, Christopher J. Gill et al.
Tropical Medicine and International Health, Article first published online 16 January 2013

15 pp. 175 kB:
http://onlinelibrary.wiley.com/doi/10.1111/tmi.12056/pdf

The authors explore what is currently known about the interactions between sickle cell disease (SCD) and malaria and review the published literature on the efficacy of malaria chemoprophylaxis in SCD. They also consider alternative strategies, including hydroxyurea, in the reduction of malaria-associated morbidity and mortality in patients with SCD.

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