The Global Enteric Multicenter Study (GEMS)

Editors: Myron M. Levine, Karen L. Kotloff, James P. Nataro et al.
Clinical Infectious Diseases, Volume 55, Supplement 4, 15 December, 2012

125 pp. 2.4 MB:
http://medschool.umaryland.edu/Research-Centers/Center-for-Vaccine-Development-%28CVD%29/Global-Enterics-Multi-Center-Study-%28GEMS%29/docs/GEMS-Supplement.asp

The Global Enteric Multicenter Study (GEMS) was designed to overcome drawbacks of earlier studies and determine the etiology and population-based burden of pediatric diarrheal disease. GEMS, which includes one of the largest case/control studies of an infectious disease syndrome ever undertaken was rolled out in 4 sites in sub-Saharan Africa (Gambia, Kenya, Mali, Mozambique) and 3 in South Asia (Bangladesh, India, Pakistan), with each site linked to a population under demographic surveillance (total approximately 467 000 child years of observation among children <5 years of age). GEMS data will guide investment and help prioritize strategies to mitigate the morbidity and mortality of pediatric diarrheal disease.

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