Population-Level Impact of Same-Day Microscopy and Xpert MTB/RIF for Tuberculosis Diagnosis in Africa

by David W. Dowdy, J. Lucian Davis, Saskia den Boon et al.
PLoS ONE 8(8): e70485 (12 August 2013)

8 pp. 555 kB:
http://www.plosone.org/article/fetchObject.action;jsessionid=AA85C657D09BDCE1BA759CA9F089A744?
uri=info%3Adoi%2F10.1371%2Fjournal.pone.0070485&representation=PDF

The authors compared the population-level reduction in TB burden over ten years achievable with implementation over two years of same-day microscopy, Xpert MTB/RIF testing, and the combination of both approaches. They conclude that scaling up novel diagnostic tests for TB and optimizing existing ones are complementary strategies that, when combined, may have substantial impact on TB epidemics in Africa.

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