Verbal autopsy as a tool for identifying children dying of sickle cell disease: a validation study conducted in Kilifi district, Kenya

by Carolyne Ndila, Evasius Bauni, Vysaul Nyirongo et al.
BMC Medicine 2014, 12:65 (22 April 2014)

21 pp. 196 kB:
http://www.biomedcentral.com/content/pdf/1741-7015-12-65.pdf

Recent studies and provisional data from this study, outlining the importance of sickle cell disease (SCD) as a cause of death in children in many parts of the developing world, contributed to the inclusion of specific SCD questions in the 2012 version of the WHO verbal autopsy (VA) instruments, and a specific code for SCD has now been included in the WHO and InterVA-4 computer-based probabilistic model cause of death (COD) listings. With these modifications, VA may provide a useful approach to quantifying the contribution of SCD to childhood mortality in rural African communities. Further studies will be needed to evaluate the generalizability of the findings beyond their local context.

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