by Helen E Jenkins, Arielle W Tolman, Courtney M Yuen et al.
The Lancet, Vol. 383, Issue 9928, pp. 1572-1579, 3 May 2014
Multidrug-resistant tuberculosis threatens to reverse recent reductions in global tuberculosis incidence. Although children younger than 15 years constitute more than 25% of the worldwide population, the global incidence of multidrug-resistant tuberculosis disease in children has never been quantified. The authors aimed to estimate the regional and global annual incidence of multidrug-resistant tuberculosis in children. They conclude that their estimates underscore that many cases of tuberculosis and multidrug-resistant tuberculosis disease are not being detected in children. Future estimates can be refined as more and better tuberculosis data and new diagnostic instruments become available.