HIV infection: epidemiology, pathogenesis, treatment, and prevention

by Gary Maartens, Connie Celum, Sharon R Lewin
The Lancet, Early Online Publication, 5 June 2014

14 pp. 952 kB:
http://download.thelancet.com/pdfs/journals/lancet/PIIS0140673614601641.pdf

HIV prevalence is increasing worldwide because people on antiretroviral therapy are living longer, although new infections decreased from 3.3 million in 2002, to 2.3 million in 2012. Global AIDS-related deaths peaked at 2.3 million in 2005, and decreased to 1.6 million by 2012. An estimated 9.7 million people in low-income and middle-income countries had started antiretroviral therapy by 2012. New insights into the mechanisms of latent infection and the importance of reservoirs of infection might eventually lead to a cure.

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