Old and new challenges in Chagas disease

by Jose A Pérez-Molina, Angela Martinez Perez, Francesca F Norman et al.
Lancet Infect Dis 2015 – Published Online July 29, 2015

10 pp. 114 kB
http://thelancet.com/pdfs/journals/laninf/PIIS1473-3099(15)00243-1.pdfcov200h_resize

Chagas disease, caused by the parasite Trypanosoma cruzi, is a neglected disease, which can lead to cardiomyopathy, arrhythmias, megaviscera, and more rarely, polyneuropathy in up to 30–40% of patients around 20 to 30 years after acute infection. Although it is endemic in the Americas, global population movements mean that it can be located wherever migrants from endemic areas settle. The report illustrates the challenges of an increasingly common infection seen in non-endemic countries, and highlights both daily management dilemmas and associated difficulties that arise.

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