Local Heat Application for the Treatment of Buruli Ulcer: Results of a Phase II Open Label Single Center Non Comparative Clinical Trial

by Moritz Vogel, Pierre F. Bayi, Marie-Thérèse Ruf et al.
Clin Infect Dis. (2016) 62 (3): 342-350.

9 pp. 850 kB
http://cid.oxfordjournals.org/content/62/3/342.full.pdf+html3.cover_resize

Buruli ulcer (BU) is a necrotizing skin disease most prevalent among West African children. The causative organism, Mycobacterium ulcerans, is sensitive to temperatures above 37°C. Local thermotherapy is therefore a highly effective, simple, cheap and safe treatment. It has in particular potential as home-based remedy for BU suspicious lesions at community level where laboratory confirmation is not available.

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