WHO Guidelines for the Treatment of Neisseria gonorrhoeae

by Nancy Santesso, Judith Wasserheit, Holger Schünemann et al.
World Health Organization, 2016

64 pp. 3.1 MB
http://www.ncbi.nlm.nih.gov/books/NBK379221/pdf/Bookshelf_NBK379221.pdfPic 001_resize

Since the publication of the WHO Guidelines for the management of sexually transmitted infections in 2003, changes in the epidemiology of STIs and advancements in prevention, diagnosis and treatment necessitate changes in STI management. There is an urgent need to update treatment recommendations for gonococcal infections to respond to changing antimicrobial resistance (AMR) patterns of N. gonorrhoeae. High-level resistance to previously recommended quinolones is widespread and decreased susceptibility to the extended-spectrum (third-generation) cephalosporins, another recommended first-line treatment in the 2003 guidelines, is increasing and several countries have reported treatment failures.

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