Guillain–Barré Syndrome Associated with Zika Virus Infection in Colombia

by Beatriz Parra, Jairo Lizarazo, Jorge A. Jiménez-Arango et al.
The New England Journal of Medicine, October 5, 2016

11 pp. 564 kB
http://www.nejm.org/doi/pdf/10.1056/NEJMoa1605564image-009

Zika virus (ZIKV) infection has been linked to the Guillain–Barré syndrome. From November 2015 through March 2016, clusters of cases of the Guillain–Barré syndrome were observed during the outbreak of ZIKV infection in Colombia. The authors characterized the clinical features of cases of Guillain–Barré syndrome in the context of this ZIKV infection outbreak and investigated their relationship with ZIKV infection. They conclude that the evidence of ZIKV infection documented by RT-PCR among patients with the Guillain–Barré syndrome during the outbreak of ZIKV infection in Colombia lends support to the role of the infection in the development of the Guillain–Barré syndrome.

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