Typhoid fever in a Tertiary Hospital in Nigeria: Another look at the Widal agglutination test as a preferred option for diagnosis

by Osahon Enabulele and Simeon Nyemike Awunor
Niger Med J. 2016 May-Jun; 57(3): 145–149

Read online at:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924394/cover

Single Widal agglutination test rather than blood culture, is commonly employed to diagnose typhoid fever in Nigeria. The authors took another look at the Widal agglutination test as a preferred option for diagnosis of typhoid fever by determining the specificity and sensitivity of Widal agglutination test in febrile adult patients. They conclude that a single Widal agglutination test is not a valid diagnostic option for typhoid fever while co-infection with malaria parasite is the preponderant microbiological finding in typhoid fever infections. The severity of malaria parasitemia is associated with positive titers on Widal test.

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