Using evolution to generate sustainable malaria control with spatial repellents

Penelope Anne Lynch and Mike Boots
eLife 2016;5:e15416

31 pp. 2.1 MB

Many of the mosquito species that transmit malaria have evolved to bite humans indoors at night, and therefore health programs target them using insecticides sprayed on surfaces inside people’s homes. This strategy, however, stops working when mosquito populations evolve to resist the insecticide used, either because they are immune to its poisonous effects or because they change their behaviour to avoid it. Consequently, there is now a need to develop alternative strategies to control mosquitoes that are more sustainable in the face of evolution. One possibility is repellents that keep mosquitoes out of homes.

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