A Multicenter Pivotal Clinical Trial of a Urine Malaria Test (UMT) for the Rapid Diagnosis of Plasmodium falciparum Malaria

by Wellington A. Oyibo, Nnenna Ezeigwe, Godwin Ntadom et al.
J. Clin. Microbiol. – Posted Online 9 November 2016

29 pp. 1.1 MB
http://jcm.asm.org/content/early/2016/11/03/JCM.01431-
16.full.pdf#page=1&view=FitH
11-cover

The need to expand malaria diagnosis alongside policy requirements for mandatory testing before treatment motivates exploration of non-invasive rapid diagnostic tests (RDTs). The authors report the outcome of the first cross-sectional, single-blind clinical performance evaluation of a Urine Malaria Test (UMT) for Plasmodium falciparum (Pf) malaria diagnosis in febrile patients. They conclude that UMT performance was comparable to BinaxNOW Pf/Pan tests, and is a promising tool to expand malaria testing in public and private healthcare settings where there are challenges to blood-based malaria diagnosis testing.

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