Validity of a Minimally Invasive Autopsy for Cause of Death Determination in Adults in Mozambique: An Observational Study

by Paola Castillo, Miguel J. Martínez, Esperança Ussene et al.
PLoS Med 13(11): e100217 – Published: November 22, 2016

15 pp. 1.5 MB
http://journals.plos.org/plosmedicine/article/file?
d=10.1371/journal.pmed.1002171&type=printable
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There is an urgent need to identify tools able to provide reliable information on the cause of death in low-income regions, since current methods (verbal autopsy, clinical records, and complete autopsies) are either inaccurate, not feasible, or poorly accepted. The authors aimed to compare the performance of a standardized minimally invasive autopsy (MIA) approach with that of the gold standard, the complete diagnostic autopsy (CDA), in a series of adults who died at Maputo Central Hospital in Mozambique. They conclude that a simple MIA procedure can identify the cause of death in many adult deaths in Mozambique. This tool could have a major role in improving the understanding and surveillance of causes of death in areas where infectious diseases are a common cause of mortality.

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