Prototype Positive Control Wells for Malaria Rapid Diagnostic Tests: Prospective Evaluation of Implementation among Health Workers in Lao People’s Democratic Republic and Uganda

by David Bell, John Baptist Bwanika, Jane Cunningham et al.
Am J Trop Med Hyg 2016 16-0498 – Published online November 29, 2016

21 pp. 1.8 MB
http://www.ajtmh.org/content/early/2016/11/29/ajtmh.16-
0498.full.pdf#page=1&view=FitH
cover

Rapid diagnostic tests (RDTs) are widely used for malaria diagnosis, but lack of quality control at point of care restricts trust in test results. Prototype positive control wells (PCW) containing recombinant malaria antigens have been developed to identify poor-quality RDT lots. This study assessed community and facility health workers’ (HW) ability to use PCWs to detect degraded RDTs, the impact of PCW availability on RDT use and prescribing, and preferred strategies for implementation in Lao People’s Democratic Republic (Laos) and Uganda.

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