Emergence of drug resistance in patients with tuberculosis cared for by the Indian health-care system: a dynamic modelling study

by Stephanie Law, Amy S Piatek, Cheri Vincent et al.
The Lancet Public Health 2016, Published Online December 18, 2016

9 pp. 105 kB
http://www.thelancet.com/pdfs/journals/lanpub/PIIS2468-2667(16)30035-4.pdf

India has the highest number of patients with tuberculosis and multidrug-resistant tuberculosis in the world. The authors used a transmission model to project the emergence of drug resistance in India due to incorrect tuberculosis management practices in multiple sectors, including public and private providers, chemists, and non-allopathic practitioners. They predict a gradual transformation from the current epidemic of drug-susceptible tuberculosis to a drug-resistant epidemic. Evidence-based strategies to improve provider practices and patient adherence across health sectors are urgently needed to prevent this.

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