How to Contain Artemisinin- and Multidrug-Resistant Falciparum Malaria

by Arjen M. Dondorp, Frank M. Smithuis, Charley Woodrow et al.
Trends in Parasitology – Published Online: February 07, 2017

11 pp. 1.9 MB
http://www.cell.com/trends/parasitology/pdf/S1471-4922(17)30004-1.pdf

In the Greater Mekong subregion (GMS), artemisinin resistance is increasingly compounded by partner drug resistance, causing high failure rates of artemisinin combination therapies in some areas. Village health workers (VHWs) play a key role in the provision of community-based services which have to reach even the most remote populations. Additional, more aggressive, approaches will be important to accelerate malaria elimination, which could include mass drug administrations, potentially in combination with ivermectin and vaccination, mass screening and treatment with novel diagnostics, reactive case detection, and other measures.

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