Viral Load (VL) testing as an HIV treatment monitoring strategy based on the latest WHO guidelines

by Tienie Stander
The quarterly update on epidemiology from the South African Centre for Epidemiological Modelling and Analysis (SACEMA), March 2017

3 pp. 274 kB
http://sacemaquarterly.com/wp-content/uploads/2017/03/Tienie_VL-testing_article-2.pdf

This study attempted to evaluate several HIV treatment monitoring strategies based on the 2013 and 2016 WHO Guidelines by developing a mathematical model that mimics the natural history of people on ART in South Africa. The results indicate that, from both a public health and an economic perspective, the replacement of HIV monitoring from the current CD4 count testing to only viral load (VL) testing, is not supported. The best economic results were achieved in the hybrid strategies combining CD4 and VL tests. More cost modelling studies are required to evaluate the cost-benefit of the 2016 WHO Guidelines.

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