Evaluation of a Mobile Phone–Based Microscope for Screening of Schistosoma haematobium Infection in Rural Ghana

by Isaac I. Bogoch, Hatice C. Koydemir, Derek Tseng et al.
The American Journal of Tropical Medicine and Hygiene; Available online: 27 March 2017

7 pp. 962 kB
http://www.ajtmh.org/content/journals/10.4269/ajtmh.16-0912?emailalert=true

The authors compared a novel, low-cost mobile phone microscope to a conventional light microscope for the label-free diagnosis of Schistosoma haematobium infections in a rural Ghanaian school setting. The mobile phone microscope had a sensitivity of 72.1% (95% confidence interval [CI]: 56.1–84.2), specificity of 100% (95% CI: 75.9–100), positive predictive value of 100% (95% CI: 86.3–100), and a negative predictive value of 57.1% (95% CI: 37.4–75.0). With its modest sensitivity and high specificity, this handheld and cost-effective mobile phone–based microscope is a stepping-stone toward developing a powerful tool in clinical and public health settings where there is limited access to conventional laboratory diagnostic support.

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