Analytical sensitivity of current best-in-class malaria rapid diagnostic tests

by Alfons Jimenez, Roxanne R. Rees-Channer, Rushini Perera et al.
Malaria Journal, 2017 16:128 – Published: 24 March 2017

9 pp. 993 kB
http://malariajournal.biomedcentral.com/track/pdf/10.1186/s12936-017-1780-5?
site=malariajournal.biomedcentral.com

Rapid diagnostic tests (RDTs) are today the most widely used method for malaria diagnosis and are recommended, alongside microscopy, for the confirmation of suspected cases before the administration of anti-malarial treatment. The diagnostic performance of RDTs, as compared to microscopy or PCR is well described but the actual analytical sensitivity of current best-in-class tests is poorly documented. This value is however a key performance indicator and a benchmark value needed to developed new RDTs of improved sensitivity.

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