by Nikhil Ranadive, Simon Kunene, Sarah Darteh et al.
Clin Infect Dis (2017) 64 (9): 1221-1227 – Published: 27 March 2017
In the low-transmission setting of Swaziland, the authors demonstrated low sensitivity of Rapid Diagnostic Tests (RDTs) for malaria diagnosis, owing to an unexpectedly high proportion of low-density infection among symptomatic subjects. The positive predictive value (PPV) was also low, requiring further investigation. A more accurate point-of-care diagnostic may be needed to support malaria elimination efforts.