Severity of Pneumonia in Under 5-Year-Old Children from Developing Countries: A Multicenter, Prospective, Observational Study

by Thomas Bénet, Valentina Sanchez Picot, Shally Awasthi et al.
The American Journal of Tropical Medicine and Hygiene – Online First, Published 01 May 2017

25 pp. 6.5 MB
http://www.ajtmh.org/deliver/fulltext/10.4269/ajtmh.16-0733/160733.pdf?
itemId=/content/journals/10.4269/ajtmh.16-
0733&mimeType=pdf&containerItemId=content/astmh

Despite reduced mortality rates in recent years, pneumonia is the foremost cause of death from infectious diseases in under 5-year-old children worldwide, accounting for 15% of total deaths, mostly in developing countries. Hypoxemia, frequently associated with pneumonia and a marker of disease severity, leads to 3- to 4-fold increased risk of death in children with pneumonia. The objectives of the present study are to assess the microbiological agents linked to hypoxemia in hospitalized children with pneumonia in developing countries, to identify clinical and para-clinical predictors of hypoxemia and to pinpoint factors associated with death within 2 weeks after admission.

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