The Impact of Systems Medicine on Human Health and Disease

Edited by Adil Mardinoglu and Jens Nielsen
Frontiers in Physiology and Frontiers in Neuroscience, 2017

98 pp. 15.2 MB
http://journal.frontiersin.org/researchtopic/3799/pdf

Systems medicine provides an integrative platform for studying the interactions between the biological components of the cell using a holistic approach and generating mechanistic explanations for the emergent systems properties. This inter-disciplinary field of study allows for understanding biological processes of cells in health and disease states, gaining new insights into what drives the appearance of the disease and finally identifying proteins and metabolites implicated in human disease. Systems medicine utilizes mathematical approaches to generate models which can be employed for designing new sets of experiments and for mapping the response of the system to perturbations quantitatively. These models as well as the developed tools can accelerate the emergence of personalized medicine which can transform the practice of medicine and offer better targets for drug development with minimum side effects.

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