A Sensitive Method for Detecting Zika Virus Antigen in Patients’ Whole-Blood Specimens as an Alternative Diagnostic Approach

by Fok-Moon Lum, Cui Lin, Olga Y Susova et al.
The Journal of Infectious Diseases, Vol. 216, Issue 2, 15 July 2017

9 pp. 2.7 MB
https://academic.oup.com/jid/article-pdf/216/2/182/19418297/jix276.pdf

Epidemics caused by the re-emergence of Zika virus (ZIKV) warrant the need to develop new diagnostic measures to complement currently used detection methods. In this study, the authors explored the detection of ZIKV antigen in a defined leukocyte subset from patients’ whole-blood specimens. Their data highlight an alternative approach in using flow cytometry as a sensitive method for detecting ZIKV antigen in whole blood.

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