The global burden of tuberculosis mortality in children: a mathematical modelling study

by Peter J Dodd, Courtney M Yuen, Charalambos Sismanidis et al.
The Lancet Global Health, Vol. 5, No. 9, e898–e906, September 2017

9 pp. 749 kB
http://www.thelancet.com/pdfs/journals/langlo/PIIS2214-109X(17)30289-9.pdf

Tuberculosis in children is increasingly recognised as an important component of the global tuberculosis burden, with an estimated 1 million cases in 2015. Although younger children are vulnerable to severe forms of tuberculosis disease, no age-disaggregated estimates of paediatric tuberculosis mortality exist, and tuberculosis has never been included in official estimates of under-5 child mortality. The authors conclude that tuberculosis is a top ten cause of death in children worldwide and a key omission from previous analyses of under-5 mortality. Almost all these deaths occur in children not on tuberculosis treatment, implying substantial scope to reduce this burden.

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