Scientists seek approval from regulators for this relatively quick and easy therapy
by Amy Maxmen
Nature 550,441,(26 October 2017)
For the first time, researchers have cured the deadly neurological disease sleeping sickness using pills instead of a combination of intravenous infusions and pills. The oral therapy — called fexinidazole — cured 91% of people with severe sleeping sickness, compared with 98% who were treated with the combination therapy. It also cured 99% of people in an early stage of the disease who would typically undergo a spinal tap to determine whether they needed infusions. The relative ease of the treatment with fexinidazole means that if approved, it might save more lives than the current option, say the investigators leading the phase 3 trial, the final phase of testing before the drug goes to regulators for approval.