Category Archives: Essential Medicines

Health-industry linkages for local health: reframing policies for African health system strengthening border

by Maureen Mackintosh; Julius Mugwagwa; Geoffrey Banda et al. Health Policy and Planning, Published: 19 March 2018 9 pp. 182 kB https://academic.oup.com/heapol/advance-article- pdf/doi/10.1093/heapol/czy022/24398759/czy022.pdf There is scepticism among health systems experts internationally that production of pharmaceuticals in sub-Saharan Africa (SSA) can … Continue reading

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The Blossoming of Contraceptive Implant Use in Africa

by Roy Jacobstein Global Health: Science and Practice March 2018, GHSP-D-17-00396 23 pp. 859 kB http://www.ghspjournal.org/content/ghsp/early/2018/03/20/GHSP-D-17-00396.full.pdf Contraceptive implant use is rising rapidly, substantially, and equitably in many sub-Saharan African countries, across almost all sociodemographic categories. Gains in implant use have … Continue reading

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Impact of Four Years of Annual Mass Drug Administration on Prevalence and Intensity of Schistosomiasis among Primary and High School Children in Western Kenya: A Repeated Cross-Sectional Study

by Bernard O. Abudho, Eric M. Ndombi, Bernard Guya et al. The American Journal of Tropical Medicine and Hygiene – Available online: 12 March 2018 17 pp. 382 kB http://www.ajtmh.org/deliver/fulltext/10.4269/ajtmh.17-0908/tpmd170908.pdf? itemId=/content/journals/10.4269/ajtmh.17- 0908&mimeType=pdf&containerItemId=content/astmh Schistosomiasis remains a major public health problem in … Continue reading

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Progress Report on Access to Hepatitis C Treatment

Focus on Overcoming Barriers in Low- and Middle-Income Countries by Françoise Renaud, Peter Beyer, Marc Bulterys et al. World Health Organization, March 2018 68 pp. 2.8 MB http://apps.who.int/iris/bitstream/10665/260445/1/WHO-CDS-HIV-18.4-eng.pdf?ua=1 A new WHO report shows that the annual number of people receiving … Continue reading

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Effect of self-administration versus provider-administered injection of subcutaneous depot medroxyprogesterone acetate on continuation rates in Malawi: a randomised controlled trial

by Holly M Burke, Mario Chen, Mercy Buluzi et al. Lancet Glob Health 2018 – Published Online March 8, 2018 11 pp. 365 kB http://www.thelancet.com/pdfs/journals/langlo/PIIS2214-109X(18)30061-5.pdf Injectable contraceptives are popular in sub-Saharan Africa but have high discontinuation rates due partly to … Continue reading

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Advanced HIV Disease

Clinical Infectious Diseases, Vol. 66, Issue suppl_2, 1 April 2018 Free Access to all articles at: https://academic.oup.com/cid/issue/66/suppl_2 There is an increasing realization that there is a persistent and large burden of human immunodeficiency virus (HIV)–associated morbidity and mortality encountered in … Continue reading

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Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised, controlled, double-blind phase 3 trial

by Nicholas O Opoku, Didier K Bakajika, Eric M Kanza et al. The Lancet, Published Online January 17, 2018 10 pp. 552 kB https://www.sciencedirect.com/science/article/pii/S0140673617328441/pdfft? md5=4117eb319b9d35aa5392b50cc5e19b2c&pid=1-s2.0-S0140673617328441-main.pdf The morbidity and socioeconomic effects of onchocerciasis, a parasitic disease that is primarily endemic in … Continue reading

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Guideline: preventive chemotherapy to control soil-transmitted helminth infections in at-risk population groups

by Antonio Montresor, Juan Pablo Peña-Rosas, Pura Rayco-Solon et al. World Health Organization, 2017 87 pp. 1.6 MB http://apps.who.int/iris/bitstream/10665/258983/1/9789241550116-eng.pdf This guideline provides global, evidence-informed recommendations on preventive chemotherapy, as a public health intervention in areas endemic for soil-transmitted helminths, to … Continue reading

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Efficacy and Safety of Fosmidomycin–Piperaquine as Nonartemisinin-Based Combination Therapy for Uncomplicated Falciparum Malaria: A Single-Arm, Age De-escalation Proof-of-Concept Study in Gabon

by Ghyslain Mombo-Ngoma, Jonathan Remppis, Moritz Sievers et al. Clinical Infectious Diseases, Published: 26 December 2017 8 pp. 521 kB https://academic.oup.com/cid/advance-article- pdf/doi/10.1093/cid/cix1122/23806493/cix1122.pdf Artemisinin-based combination therapy (ACT) has made a major contribution to reducing the global malaria burden, but its role … Continue reading

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SAGE Yellow Book: Strategic Advisory Group of Experts on Immunization (SAGE)

17 – 19 October 2017 Executive Boardroom, WHO HQ, Geneva 472 pp. 30.9 MB(!) http://www.who.int/immunization/sage/meetings/2017/october/Yellow_book_SAGE_O ctober_2017.pdf?ua=1 SAGE Working Groups are established as resources intended to increase the effectiveness of SAGE deliberations by reviewing and providing evidence-based information and options for … Continue reading

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